Episode 3: Hyperoxia



Hello and welcome to our next episode – we hope you enjoy it. This episode concentrates on hyperoxia – the delivery of lots (often too much) oxygen and the harms it may cause our patients. We both had colds – many apologies for the blocked noses and many sniffs!

We hope you find it useful.

To follow: Dr Matt Thomas from the Great Western Air Ambulance discussing his groups work around reducing hyperoxia post-rosc.

Further reading:

  1.  https://www.brit-thoracic.org.uk/guidelines-and-quality-standards/
  2. Cornet AD, Kooter AJ, Peters MJL, Smulders YM. The potential harm of oxygen therapy in medical emergencies. Crit Care. 2013 Apr 11;17(2):313.
  3. Rincon F, Kang J, Maltenfort M, Vibbert M, Urtecho J, Athar MK, et al. Association Between Hyperoxia and Mortality After Stroke. Crit Care Med. 2014 Feb;42(2):387–96.
  4. Stub D, Smith K, Bernard S, Bray J, Stephenson M, Cameron P, et al. A randomized controlled trial of oxygen therapy inacute myocardial infarction Air Verses Oxygen InmyocarDial infarction study (AVOID Study). American Heart Journal. Mosby, Inc; 2012 Mar 1;163(3):339–345.e1. 3.    Asfar P, Singer M, Radermacher P. Understanding the benefits and harms of oxygen therapy. Intensive Care Med. 2015 Jan 30.
  5. Calzia E, Asfar P, Hauser B, Matejovic M, Ballestra C, Radermacher P, et al. Hyperoxia may be beneficial. Crit Care Med. 2010 Oct;38:S559–68.
  6. Asfar P, Calzia E, Huber-Lang M, Ignatius A, Radermacher P. Hyperoxia during septic shock–Dr. Jekyll or Mr. Hyde? Shock. 2011 Nov 21;37(1):122–3.
  7. Cornet AD, Kooter AJ, Peters MJL, Smulders YM. The potential harm of oxygen therapy in medical emergencies. Crit Care. 2013 Apr 11;17(2):313.
  8. Ligtenberg JJM, Stolmeijer R, Broekema JJ, Maaten ter JC, Zijlstra JG. A little less saturation? Crit Care. 2013 Jun 12;17(3):439.


How to cite this podcast:

Nutbeam T, Bosanko C. Hyperoxia. PHEMCAST. 2015 [cite Date Accessed]. Available from: http://www.phemcast.co.uk

5 thoughts on “Episode 3: Hyperoxia

  1. Pingback: Episode 3: Hyperoxia | Prehospital and Retrieval Medicine - THE PHARM dedicated to the memory of Dr John Hinds

  2. Great stuff, thank you – something I’d been pondering at work for a while. It’s worth highlighting that while hyperoxia may cause harm, hypoxia is associated with worse outcome in brain injury (only trumped by hypotension). See Brain Trauma Foundation Guidelines for 2007 – getting rather old now, but still. If I injured my brain I think I’d have some oxygen, please – I’d chance the potential harm of hyperoxia to make as sure as possible that I didn’t suffer any spells of hypoxia, until transport monitoring is infallible.


  3. Couldn’t agree more. There is a fine balance that we need to get right. Oxygen is a drug which should be appropriately used and easy (lazy!) care – leaving them on an FiO2 of 1 is probably not the right thing for everybody – we’re working on a podcast now on patients which require oxygen and how to deliver it! Thanks for your comment!


  4. Thanks for your podcast. Just highlights again that resuscitation is an intelligent process and that one size doesn’t fit all.


  5. Pingback: Papers of April | Emergency Medicine Podcasts

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